Dr Soban Sadiq

About

Soban completed his medical degree (MBBS) and MPhil (Clinical Pharmacology) from Pakistan. He worked in hospital as medical registrar in department of medicine. During working in hospital, he got interest in research especially in type 2 diabetes. To excel in research, he got opportunity to study in University of Liverpool-UK from where he obtained his PhD degree in Molecular and Clinical Pharmacology. He later worked in Imperial College London as Clinical Pharmacology Lead. He has vast experience of Teaching and Research and published papers in national and international journals. He is also Fellow of higher education academy (FHEA) and academy of medical educators (FAcadMEd). His main research interests revolve around drugs-induced metabolic syndrome including cardiovascular disease and type 2 diabetes. He worked mainly on antipsychotic and anticancer drugs and interested in exploring other drugs leading to metabolic syndrome.

Research interests

The focus of Soban’s research is on drugs-induced metabolic toxicities including diabetes and obesity. His special focus is on antipsychotics and anticancer induced metabolic toxicities. However, he is looking forward to study other drugs as well. His PhD research has shown the role of adipokines and lipids as potential underlying mechanisms causing drugs-induced metabolic toxicities. In vitro data from his research also showed potential drugs to reverse these metabolic toxicities which need further evaluation leading to clinical trials.

He is also interested in exploring the cross-talk between adipocytes and cancer. Few studies have shown the role of adipocytes and adipokines (tumour microenvironment) in cancer. Detailed research required to explore how cancer cells interact with adipocytes leading to tumour progression and dissemination. He is also interested in medical education-related research and has special interest in Team-based learning and learning in metaverse environment.

Teaching

Soban’s main subject of teaching is in Clinical Pharmacology. He has vast experience of teaching to undergraduate and postgraduate students. He has interest in Team-based learning and teaching Pharmacology in metaverse platform.

Professional

1. Fingolimod (FTY720) Preserves High Energy Phosphates and Improves Cardiac Function in Heterotopic Heart Transplantation Model.
Ahmed N, Farooq J, Sadiq S, Meo SA, Jan A, Cheema FH, Faggian G, Rungatscher A.Int J Mol Sci. 2020 Sep 8;21(18):6548. doi: 10.3390/ijms21186548. (Impact factor: 5.9)

2. Cardioprotective Effects of Sphingosine-1-Phosphate Receptor Immunomodulator FTY720 in a Clinically Relevant Model of Cardioplegic Arrest and Cardiopulmonary Bypass. Ahmed N, Mehmood A, Linardi D, Sadiq S, Tessari M, Meo SA, Rehman R, Hajjar WM, Muhammad N, Iqbal MP, Gilani AU, Faggian G, Rungatscher A. Front Pharmacol. 2019 Jul 18;10:802. doi: 10.3389/fphar.2019.00802.(Impact factor: 4.4)

3. Nilotinib-induced metabolic dysfunction: insights from a translational study using in vitro adipocyte models and patient cohorts.
Sadiq S, Owen E, Foster T, Knight K, Wang L, Pirmohamed M, Clark RE, Pushpakom S. Leukemia. 2019 Jul;33(7):1810-1814. doi: 10.1038/s41375-018-0337-0. (Impact factor: 11.5)